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So, JANUVIA works more when you need it and less when you don't Januvia (generic name: sitagliptin) is a prescription oral diabetes tablet taken once daily, along with diet and exercise, to help to lower blood sugar levels (glucose) in adults living with type 2 diabetes. Januvia Prescription Assistance. Januvia is used to lower blood sugar levels in patients with type 2 diabetes mellitus JANUVIA is a dipeptidyl peptidase-4 (DPP-4) inhibitor indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. JANUVIA is a dipeptidyl peptidase-4 (DPP-4) inhibitor indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. JANUVIA (jah-NEW-vee-ah) is a once-daily prescription pill that, along with diet and exercise, helps lower blood sugar levels in adults with type 2 diabetes. JANUVIA should not be used in patients with type 1 diabetes JANUVIA is a once-daily prescription pill. 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